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BSF Enterprise PLC

BSF Enterprise Pioneering the Future of Bio-Sustainability

Turning pioneering biotechnology into focused commercial businesses

BSF Enterprise is a life sciences platform. 3D Bio-Tissues develops and owns the Group’s core technology, and our companies take it to market.

3D Bio-Tissues at the centre, supplying technology to Lab-Grown Leather, Kerato and milieu.bio 3D Bio-Tissues IP & manufacturing Kerato Corneal repair Lab-Grown Leather Luxury & automotive materials milieu.bio Cell-culture media

A welcome from our CEO

Dr Che Connon, Chief Executive Officer of BSF Enterprise

Dr Che Connon

Chief Executive Officer, BSF Enterprise PLC

Welcome to BSF Enterprise’s investor website, and thank you for your interest in what we are building.

Our aim is to grow high-quality tissue and materials from cells, as an alternative to sources that today depend on animals or human donors.

At the heart of the Group is 3D Bio-Tissues, our research and IP company in Newcastle upon Tyne. Its tissue-engineering platform uses macromolecular crowding to help cells lay down their own natural matrix.

From that platform, our companies are taking the technology into several markets: leather for luxury fashion and automotive interiors through Lab-Grown Leather, corneal repair through Kerato, and cell-culture media supplements through milieu.bio. ETSYL®, our collagen-stimulating peptide, is licensed for skincare. 3D Bio-Tissues has also filed a patent application for seamless tissue coverings for humanoid robot hands.

This site is built for our shareholders and anyone considering investing. You can read every announcement, watch updates from the team and ask questions on any piece of news. Please do send yours. My team and I read them all and will reply wherever we can.

Platform news

BSF expands into humanoid robotics

3D Bio-Tissues has filed a priority patent application (GB2622781.9) for moulding tissue into a single, seamless 3D piece, including coverings for humanoid robot hands. It is the same stitchless architecture already in partner-funded evaluation programmes with two leading luxury fashion houses through Lab-Grown Leather.

  • One continuous covering, with no glued seams to fail
  • Footwear-grade wear resistance over the finger pads, thinning to 0.3 mm over the joints
  • To be developed with robotics manufacturers through partner-funded agreements

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As seen in Vogue

T-Rex Leather™in fine jewellery

CFDA/Vogue Fashion Fund 2026 · Material Innovation Challenge

Lab-Grown Leather Ltd, part of the BSF group, was one of 14 material innovators in the 2026 CFDA/Vogue Fashion Fund Material Innovation Challenge. Finalist George Inaki of MILAMORE made the Kintsugi Heart, a T-Rex Leather™ cuff with a broken-heart clasp in 18k gold, silver and natural diamonds, featured by Vogue.

T-Rex Leather™ is grown from a collagen sequence reconstructed from fossil protein evidence: one application of the group's tissue-engineering platform.

T-Rex Leather™ and IMPOSTER 4 Animals, designed by George Inaki for MILAMORE. T-Rex Leather™ made by Lab-Grown Leather Ltd (ATEP™ platform), with The Organoid Company and VML.

Discover more about our company structure

How 3D Bio-Tissues and our operating companies, Lab-Grown Leather, Kerato and milieu.bio, fit together.

See our structure
Patent news

US patent allowance for macromolecular crowding technology

The USPTO has issued a Notice of Allowance for US Patent Application No. 18/578,286, "Cell culture medium and supplements for corneal and skin cell culture," held by 3D Bio-Tissues. All 17 examined claims have been allowed, covering serum-free and reduced-serum media formulations that use 3D Bio-Tissues’ proprietary macromolecular crowding agents.

On issuance, the patent will protect the technology behind CityMix® and CytoBoost™, which milieu.bio sells under licence from 3D Bio-Tissues. The claims also cover the skin cell culture and matrix deposition used in Lab-Grown Leather’s production route, and support long-term cell-based options for Kerato.

Related announcement Foundational US Patent Underpins Business Strategy

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Patent news

US patent allowance for ETSYL® technology

The USPTO has issued a Notice of Allowance for US Patent Application No. 17/782,948, "Collagen Production," held by 3D Bio-Tissues. The allowed claims cover methods using ETSYL® (palmitoyl pentapeptide-87) to stimulate and enhance collagen production in cells.

On issuance, the patent will strengthen 3D Bio-Tissues’ IP position in the United States, a major market for anti-ageing skincare and bioactive peptides. It supports the worldwide exclusive commercialisation agreement with SCHAKAU for ETSYL® in cosmetics and luxury beauty.

Related announcement Key US Patent for ETSYL® Technology

Patent details

Application US 17/782,948
Title Collagen Production
Holder 3D Bio-Tissues
Status Notice of Allowance (USPTO)
Licensee SCHAKAU, worldwide exclusive, cosmetics and luxury beauty

A portfolio curated through deep scientific insight

Giving investors access to next-generation innovation with an ethical approach.

  • Regenerative medicine
  • Sustainable biomaterials
  • Cellular agriculture
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Exploring cell-grown skin for robots

Robots are getting smarter and more agile, but they still meet the world through their outer surface. 3D Bio-Tissues is exploring whether its cell-grown tissue could give robot makers an alternative to the synthetic coverings they use today.

Today

Synthetic elastomers

Silicones, polyurethanes and synthetic rubbers cover most humanoid and autonomous robots. In continuous use they can wear and degrade, especially at the joints.

What we are exploring

Cell-grown tissue

3DBT’s platform grows tissue from cells, which lay down their own natural matrix. The research question is whether its natural flexibility can hold up better where synthetic coverings are under most strain.

A 3D Bio-Tissues researcher holds a cell-grown tissue sample in the lab
A 3D Bio-Tissues researcher with a cell-grown tissue sample.

Invest in next-generation tissue engineering through BSF Enterprise

One listed company, one core technology platform and three operating companies taking it to market.

Why invest

T-Rex Leather™: the story and the impact

T-Rex Leather™ made by Lab-Grown Leather Ltd, with The Organoid Company and VML.